1 in 3 seniors dies with Alzheimerâ€™s disease or another form of dementia, but as WHCUâ€™s Pete Blanchard reports, a researcher at Weill Cornell Medical College has helped discover what could be a groundbreaking new approach to how doctors treat the disease.
A team of researchers from Columbia Univeristy, Brandies University and Weill Cornell Medical College have come up with a new approach to the treatment of Alzheimerâ€™s disease.
It involves strengthening a protein complex called retromer, which research shows is deficient in the brains of patients with Alzheimerâ€™s disease.
â€śPeople who are susceptible to Alzheimerâ€™s disease and Parkinsonâ€™s disease appear to have less retromer than they should, says Dr. Gregory Petsko, a neurology professor at Weill Cornell Medical College.
He and researchers have found a new class of compounds that can stabilize the retromer protein, thereby defending the body against Alzheimerâ€™s.
â€śThink of this drug as molecular scotch tape, sticking two of the seams of retromer to keep it more stable longer,â€ť he said.
Dr. Petsko says neurological disease like Alzheimerâ€™s are going to be an epidemic in the United States as the population ages, and that biomedical research on the issue must continue.
“Itâ€™s very important that people are aware this problem is serious and going to get more serious for the U.S. and the rest of the world,” he said. “Itâ€™s very important that biomedical research continue to try and find that answer to this problem.”